RegenOss
Flexible bone substitute
Engineered for orthopaedic surgery
- Chemical and structural biomimetism
- Cell-mediated resorption leading to 3D bone regeneration Optimal handling
- Flexible and formable to the contour of the defect
Biomimetic nano-structure: as modelled in nature
Bioceramic - collagen: synergetic power
RegenOss represents an innovative concept in bone grafting. It is a collagen-hydroxyapatite composite biomaterial designed and engineered at macro-, micro-, and nano-scale to promote bone regeneration.
RegenOss is a fully biomimetic scaffold, its unique structure and chemical composition confer characteristics replicating that of human bone.
By using nature as a model, the patented nucleation of magnesium-enriched hydroxyapatite nano-crystals into type I collagen fibers resembles the process occurring during biological neo-ossification.
RegenOss is a fully biomimetic scaffold, its unique structure and chemical composition confer characteristics replicating that of human bone.
By using nature as a model, the patented nucleation of magnesium-enriched hydroxyapatite nano-crystals into type I collagen fibers resembles the process occurring during biological neo-ossification.
Replaced by new bone
RegenOss is highly hydrophilic; it can quickly absorb the biological fluids, molecules and cells promoting bone formation. Its architecture favors cells attachment and proliferation. While serving as a scaffold to guide effective bone regeneration, RegenOss is resorbed by enzymes and cellular action over a period of 6-12 months.
RegenOss strip is flexible once wet
RegenOss replaced by trabecular bone at 6 months post-op in sheep tibia model (Toluidine blue/Fast Green staining)
Trabecular bone formation at 6 months post-op in sheep tibia model (Polarized light microscopy)
Strongly positive collagen type I immunostaining at 6 months post-op, evidencing newly-formed bone development
Clinical Applications
- Distal femoral fracture
- Acetabular defect filling
- Spine fusion



RegenOss is not intended to modify or replace standard procedures for the treatment of bone defects, but for filling bony voids or gaps of the skeletal system, that are not intrinsic to the stability of the bony structure. RegenOss must be used with appropriate stabilising hardware.