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Orthobiologics

Repros

What is Repros?

Repros is a biocompatible, resorbable, synthetic bone void filler. Its composition is 60% hydroxy-apatite (HA) and 40% ß-tricalciumphosphate (ß-TCP) in a porous matrix form similar to that of cancellous bone, which provides an ideal structural environment for new bone growth. Repros acts as a temporary scaffold and is not intended to provide mechanical support during the healing process. Repros granules or blocks should preferably be soaked in bone marrow aspirate, platelet-rich plasma or blood, before being introduced into the defect by hand, maximising the bone-implant interface. Repros granules may be gently tamped into place. Repros blocks may be shaped to accurately fit the defect. If using as a bone graft extender Repros granules should be mixed well with autograft.

Safe and Reliable

Repros a gamma sterilised product, available in unlimited quantities. The biocompatibility and clinical efficacy of HA and ß-TCP as bone substitute materials is supported by over 3,000 publications and over 500 clinical studies with 25 years of successful use.

Resorption

At 12 weeks osteoclastic resorption can be clearly observed, the implant has a distinctly blurred outline with highly microporous surface. Bone remodelling continues until the implant is completely resorbed.

Osteoconductivity

Repros has 80% porosity, providing a matrix for bone in-growth without significantly altering the natural bone density. It is highly microporous (10um – 0.1 um) allowing for fluid/nutrient transfer to feed the ingrowing tissues. There is rapid bone ingrowth throughout, and around, the ultra porous granules without restriction by the material. Repros® provides longer and better osteoconductive support compared to calcium sulphate and pure TCP based products, whilst the ultra high porosity ensures that the more controlled resorption profile does not delay the healing process.

Areas of application

  • Augmentation in simple and comminuted fracture repair
  • Filling of voids after removal of osteosynthesis implants
  • Grafting of fracture non-unions
  • Treating bone defects in pelvis, long bones and extremities
  • Benign bone lesions, bone cysts, and acting as a bone graft extender where large amounts of autograft are required e.g. tumour resection.
  • Revision of joint arthroplasty: to fill gaps around prostheses providing a scaffold for the host bone
  • Spinal fusion: as a bone extender with autograft or to pack inside rigid spinal cages

 

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